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Conserved amino acids in the region connecting membrane spanning domain 1 to nucleotide binding domain 1 are essential for expression of the MRP1 (ABCC1) transporter

Multidrug resistance protein 1 (MRP1) (gene symbol ABCC1) is an ATP-binding cassette (ABC) transporter which effluxes xeno- and endobiotic organic anions including estradiol glucuronide and the pro-inflammatory leukotriene C(4). MRP1 also confers multidrug resistance by reducing intracellular drug a...

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Vydáno v:PLoS One
Hlavní autoři: Smith, Emma E., Conseil, Gwenaëlle, Cole, Susan P. C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877750/
https://ncbi.nlm.nih.gov/pubmed/33571281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246727
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