Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities

BACKGROUND: Atherosclerosis is a chronic vascular disease posing a great threat to public health. We investigated whether rosuvastatin (RVS) enhanced autophagic activities to inhibit lipid accumulation and polarization conversion of macrophages and then attenuate atherosclerotic lesions. METHODS: Al...

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Publicado en:J Transl Med
Autores principales: Zhang, Xinxin, Qin, Yating, Wan, Xiaoning, Liu, Hao, Lv, Chao, Ruan, Weibin, He, Lin, Lu, Li, Guo, Xiaomei
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877030/
https://ncbi.nlm.nih.gov/pubmed/33568202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02727-3
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