Rosuvastatin exerts anti-atherosclerotic effects by improving macrophage-related foam cell formation and polarization conversion via mediating autophagic activities

BACKGROUND: Atherosclerosis is a chronic vascular disease posing a great threat to public health. We investigated whether rosuvastatin (RVS) enhanced autophagic activities to inhibit lipid accumulation and polarization conversion of macrophages and then attenuate atherosclerotic lesions. METHODS: Al...

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發表在:J Transl Med
Main Authors: Zhang, Xinxin, Qin, Yating, Wan, Xiaoning, Liu, Hao, Lv, Chao, Ruan, Weibin, He, Lin, Lu, Li, Guo, Xiaomei
格式: Artigo
語言:Inglês
出版: BioMed Central 2021
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7877030/
https://ncbi.nlm.nih.gov/pubmed/33568202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02727-3
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