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Genomic characterization of relapsed acute myeloid leukemia reveals novel putative therapeutic targets

Relapse is the leading cause of death of adult and pediatric patients with acute myeloid leukemia (AML). Numerous studies have helped to elucidate the complex mutational landscape at diagnosis of AML, leading to improved risk stratification and new therapeutic options. However, multi–whole-genome st...

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Pubblicato in:Blood Adv
Autori principali: Stratmann, Svea, Yones, Sara A., Mayrhofer, Markus, Norgren, Nina, Skaftason, Aron, Sun, Jitong, Smolinska, Karolina, Komorowski, Jan, Herlin, Morten Krogh, Sundström, Christer, Eriksson, Anna, Höglund, Martin, Palle, Josefine, Abrahamsson, Jonas, Jahnukainen, Kirsi, Munthe-Kaas, Monica Cheng, Zeller, Bernward, Tamm, Katja Pokrovskaja, Cavelier, Lucia, Holmfeldt, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876890/
https://ncbi.nlm.nih.gov/pubmed/33560403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020003709
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