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What Is Abnormal in Normal Karyotype Acute Myeloid Leukemia in Children? Analysis of the Mutational Landscape and Prognosis of the TARGET-AML Cohort

Normal karyotype acute myeloid leukemia (NK-AML) constitutes 20–25% of pediatric AML and detailed molecular analysis is essential to unravel the genetic background of this group. Using publicly available sequencing data from the TARGET-AML initiative, we investigated the mutational landscape of NK-A...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Herlin, Morten Krogh, Yones, Sara A., Kjeldsen, Eigil, Holmfeldt, Linda, Hasle, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224370/
https://ncbi.nlm.nih.gov/pubmed/34064268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12060792
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