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Constitutive activation of NF-κB during early bone marrow development results in loss of B cells at the pro-B-cell stage

There is a considerable body of work exploring the role of NF-κB family of transcription factors in the maturation and functions of later stage B cells; however, their role in the earlier bone marrow stages of development is less well understood despite the demonstration that NF-κB activity is prese...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Paun, Andrea, Claudio, Estefania, Siebenlist, Ulrich K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876872/
https://ncbi.nlm.nih.gov/pubmed/33560391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002932
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