Alpha‐synuclein dynamics in induced pluripotent stem cell‐derived dopaminergic neurons from a Parkinson’s disease patient (PARK4) with SNCA triplication

Parkinson's disease (PD) is a neurodegenerative disorder caused by the selective loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Lewy bodies (LBs), another histological hallmark of PD, are observed in patients with familial or sporadic PD. The therapeutic potentia...

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Udgivet i:FEBS Open Bio
Main Authors: Fukusumi, Hayato, Togo, Kazuyuki, Sumida, Miho, Nakamori, Masayuki, Obika, Satoshi, Baba, Kousuke, Shofuda, Tomoko, Ito, Daisuke, Okano, Hideyuki, Mochizuki, Hideki, Kanemura, Yonehiro
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876504/
https://ncbi.nlm.nih.gov/pubmed/33301617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13060
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