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Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting

The Golgi‐localized, gamma‐ear containing, ADP‐ribosylation factor‐binding proteins (GGAs 1, 2, and 3) are multidomain proteins that bind mannose 6‐phosphate receptors (MPRs) at the Golgi and play a role, along with adaptor protein complex 1 (AP‐1), in the sorting of newly synthesized lysosomal hydr...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Doray, Balraj, Liu, Lin, Lee, Wang‐Sik, Jennings, Benjamin C., Kornfeld, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876502/
https://ncbi.nlm.nih.gov/pubmed/33206455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13040
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