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Pharmacokinetics and Pharmacodynamics of Immediate- and Modified-Release Mycophenolic Acid Preparations in Healthy Beagle Dogs

Background: Mycophenolic acid (MPA) is a broad-acting immunomodulating agent that may be therapeutically beneficial for the treatment of immune-mediated diseases in canine patients. Objectives: To determine the suppressive effects of MPA on T-cell proliferation, and to assess the feasibility of a ca...

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Publicat a:Front Vet Sci
Autors principals: Klotsman, Michael, Coquery, Sebastien, Sathyan, Gayatri, Naageshwaran, Vatsala, Shivanand, Paddy, Fairchild, Amanda J., Garden, Oliver A., Anderson, Wayne H.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876310/
https://ncbi.nlm.nih.gov/pubmed/33585601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2020.611404
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