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Effect of OROS® controlled-release delivery on the pharmacokinetics and pharmacodynamics of oxybutynin chloride

AIMS: Dry mouth is a common side-effect seen with immediate-release oxybutynin (IR-Oxy). Ditropan XL® [(Oxy-XL), a controlled-release formulation of oxybutynin chloride, is a once-daily oral dosage form that incorporates the OROS® technology. Dry mouth as the pharmacodynamic measure was compared bet...

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Detalhes bibliográficos
Main Authors: Sathyan, Gayatri, Chancellor, Michael B, Gupta, Suneel K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014596/
https://ncbi.nlm.nih.gov/pubmed/11678784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01463.x
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