Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone

BACKGROUND: The purpose of this study was investigate the dose proportionality of a novel, once-daily, controlled-release formulation of hydromorphone that utilizes the OROS(® )Push-Pull™ osmotic pump technology. METHODS: In an open-label, four-way, crossover study, 32 healthy volunteers were random...

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Detaylı Bibliyografya
Asıl Yazarlar: Sathyan, Gayatri, Xu, Emily, Thipphawong, John, Gupta, Suneel K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808051/
https://ncbi.nlm.nih.gov/pubmed/17270058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-7-3
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