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Pharmacokinetic investigation of dose proportionality with a 24-hour controlled-release formulation of hydromorphone
BACKGROUND: The purpose of this study was investigate the dose proportionality of a novel, once-daily, controlled-release formulation of hydromorphone that utilizes the OROS(® )Push-Pull™ osmotic pump technology. METHODS: In an open-label, four-way, crossover study, 32 healthy volunteers were random...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808051/ https://ncbi.nlm.nih.gov/pubmed/17270058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-7-3 |
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