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Is Senescence-Associated β-Galactosidase a Reliable in vivo Marker of Cellular Senescence During Embryonic Development?

During vertebrate embryonic development, cellular senescence occurs at multiple locations. To date, it has been accepted that when there has been induction of senescence in an embryonic tissue, β-galactosidase activity is detectable at a pH as high as 6.0, and this has been extensively used as a mar...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: de Mera-Rodríguez, José Antonio, Álvarez-Hernán, Guadalupe, Gañán, Yolanda, Martín-Partido, Gervasio, Rodríguez-León, Joaquín, Francisco-Morcillo, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876289/
https://ncbi.nlm.nih.gov/pubmed/33585480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.623175
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