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Is senescence-associated β-galactosidase a marker of neuronal senescence?

One of the features of cellular senescence is the activity of senescence-associated- β-galactosidase (SA-β-gal). The main purpose of this study was to evaluate this marker of senescence in aging neurons. We found that cortical neurons exhibited noticeable SA-β-gal activity quite early in culture. Ma...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Piechota, Malgorzata, Sunderland, Piotr, Wysocka, Adrianna, Nalberczak, Maria, Sliwinska, Malgorzata A., Radwanska, Kasia, Sikora, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348379/
https://ncbi.nlm.nih.gov/pubmed/27768595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12752
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