Early Renal Vasodilator and Hypotensive Action of Epoxyeicosatrienoic Acid Analog (EET-A) and 20-HETE Receptor Blocker (AAA) in Spontaneously Hypertensive Rats

Cytochrome P450 (CYP-450) metabolites of arachidonic acid: epoxyeicosatrienoic acids (EETs) and 20-hydroxyeicosatetraenoic acid (20-HETE) have established role in regulation of blood pressure (BP) and kidney function. EETs deficiency and increased renal formation of 20-HETE contribute to hypertensio...

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Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Walkowska, Agnieszka, Červenka, Luděk, Imig, John D., Falck, John R., Sadowski, Janusz, Kompanowska-Jezierska, Elżbieta
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Physiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876274/
https://ncbi.nlm.nih.gov/pubmed/33584348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.622882
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