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A Novel Branched DNA-Based Flowcytometric Method for Single-Cell Characterization of Gene Therapy Products and Expression of Therapeutic Genes

Many preclinical and clinical studies of hematopoietic stem cell-based gene therapy (GT) are based on the use of lentiviruses as the vector of choice. Assessment of the vector titer and transduction efficiency of the cell product is critical for these studies. Efficacy and safety of the modified cel...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Immunol
Egile Nagusiak: Garcia-Perez, Laura, van Eggermond, Marja C.J.A., Maietta, Elisa, van der Hoorn, Marie-Louise P., Pike-Overzet, Karin, Staal, Frank J. T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876092/
https://ncbi.nlm.nih.gov/pubmed/33584681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.607991
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