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Alternative lengthening of telomeres in molecular subgroups of paediatric high-grade glioma
PURPOSE: The maintenance of telomere length prevents cancer cell senescence and occurs via two mutually exclusive mechanisms: (a) reactivation of telomerase expression and (b) activation of alternative lengthening of telomeres (ALT). ALT is frequently related to alterations on ATRX, a chromatin-remo...
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| Veröffentlicht in: | Childs Nerv Syst |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Berlin Heidelberg
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7875853/ https://ncbi.nlm.nih.gov/pubmed/33128602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00381-020-04933-8 |
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