Alternative lengthening of telomeres in molecular subgroups of paediatric high-grade glioma

PURPOSE: The maintenance of telomere length prevents cancer cell senescence and occurs via two mutually exclusive mechanisms: (a) reactivation of telomerase expression and (b) activation of alternative lengthening of telomeres (ALT). ALT is frequently related to alterations on ATRX, a chromatin-remo...

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Publicado en:Childs Nerv Syst
Autores principales: Minasi, Simone, Baldi, Caterina, Gianno, Francesca, Antonelli, Manila, Buccoliero, Anna Maria, Pietsch, Torsten, Massimino, Maura, Buttarelli, Francesca Romana
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875853/
https://ncbi.nlm.nih.gov/pubmed/33128602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00381-020-04933-8
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