A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes

Skeletal muscle insulin resistance is the earliest defect in type 2 diabetes (T2D), preceding and predicting disease development. To what extent this reflects a primary defect or is secondary to tissue crosstalk due to changes in hormones or circulating metabolites is unknown. To address this questi...

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Publicado en:Cell Metab
Main Authors: Batista, Thiago M., Jayavelu, Ashok Kumar, Albrechtsen, Nicolai J. Wewer, Iovino, Salvatore, Lebastchi, Jasmin, Pan, Hui, Dreyfuss, Jonathan, Krook, Anna, Zierath, Juleen R., Mann, Matthias, Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875546/
https://ncbi.nlm.nih.gov/pubmed/32888406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2020.08.007
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