Application of a plasmin generation assay to define pharmacodynamic effects of tranexamic acid in women undergoing cesarean delivery

BACKGROUND: Tranexamic acid (TXA) is used to reduce bleeding. TXA inhibits plasmin(ogen) binding to fibrin and reduces fibrinolysis. TXA antifibrinolytic activity is typically measured by clot lysis assays; however, effects on plasmin generation (PG) are unclear due to a lack of tools to measure PG...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Thromb Haemost
मुख्य लेखकों: Miszta, Adam, Ahmadzia, Homa K., Luban, Naomi L. C., Li, Shuhui, Guo, Dong, Holle, Lori A., Berger, Jeffrey S., James, Andra H., Gobburu, Jogarao V. S., van den Anker, John, de Laat, Bas, Wolberg, Alisa S.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875467/
https://ncbi.nlm.nih.gov/pubmed/33001565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15114
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