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MED19 alters AR occupancy and gene expression in prostate cancer cells, driving MAOA expression and growth under low androgen

Androgen deprivation therapy (ADT) is a mainstay of prostate cancer treatment, given the dependence of prostate cells on androgen and the androgen receptor (AR). However, tumors become ADT-resistant, and there is a need to understand the mechanism. One possible mechanism is the upregulation of AR co...

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Bibliografiska uppgifter
I publikationen:PLoS Genet
Huvudupphovsmän: Weber, Hannah, Ruoff, Rachel, Garabedian, Michael J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875385/
https://ncbi.nlm.nih.gov/pubmed/33513133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008540
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