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The Unique Molecular Choreography of Giant Pore Formation by the Cholesterol-Dependent Cytolysins of Gram-Positive Bacteria

The mechanism by which the cholesterol-dependent cytolysins (CDCs) assemble their giant β-barrel pore in cholesterol-rich membranes has been the subject of intense study in the past two decades. A combination of structural, biophysical, and biochemical analyses has revealed deep insights into the se...

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Pubblicato in:Annu Rev Microbiol
Autori principali: Tweten, Rodney K., Hotze, Eileen M., Wade, Kristin R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875328/
https://ncbi.nlm.nih.gov/pubmed/26488276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-micro-091014-104233
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