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Membrane Tension Gates ERK-Mediated Regulation of Pluripotent Cell Fate

Cell fate transitions are frequently accompanied by changes in cell shape and mechanics. However, how cellular mechanics affects the instructive signaling pathways controlling cell fate is poorly understood. To probe the interplay between shape, mechanics, and fate, we use mouse embryonic stem cells...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: De Belly, Henry, Stubb, Aki, Yanagida, Ayaka, Labouesse, Céline, Jones, Philip H., Paluch, Ewa K., Chalut, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875115/
https://ncbi.nlm.nih.gov/pubmed/33217323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2020.10.018
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