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Mammalian Target of Rapamycin Signaling Enhances Ovalbumin-Induced Neutrophilic Airway Inflammation by Promoting Th17 Cell Polarization in Murine Noneosinophilic Asthma Model

Background: T helper 17 (Th17) is regarded as key immune cell in the pathogenesis of noneosinophilic asthma (NEA) due to the recruitment of neutrophils into the airways. The mammalian target of rapamycin (mTOR) is an important signaling molecule that plays a critical role in immune regulation. This...

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Publicat a:Pediatr Allergy Immunol Pulmonol
Autors principals: Wu, Jinhong, Zhong, Wenwei, Zhang, Hao, Yin, Yong
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc., publishers 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7875112/
https://ncbi.nlm.nih.gov/pubmed/33406024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ped.2019.1088
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