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SPARC Knockdown Reduces Glutamate-Induced HT22 Hippocampal Nerve Cell Damage by Regulating Autophagy

Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein involved in the extracellular matrix and interactions between cells during neural development of the central nervous system (CNS). Oxidative glutamate toxicity is involved in CNS diseases, including epilepsy, Alzheimer’s...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Chen, Shuang, Zou, Qin, Guo, Qiang, Chen, Yongmin, Kuang, Xi, Zhang, Yukang, Liu, Yan, Wu, Wengang, Li, Ge, Tu, Linzhi, Tong, Jingyi, Li, Songrong, Ma, Lin, Li, Qifu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7874057/
https://ncbi.nlm.nih.gov/pubmed/33584170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.581441
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