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SPARC Knockdown Reduces Glutamate-Induced HT22 Hippocampal Nerve Cell Damage by Regulating Autophagy

Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein involved in the extracellular matrix and interactions between cells during neural development of the central nervous system (CNS). Oxidative glutamate toxicity is involved in CNS diseases, including epilepsy, Alzheimer’s...

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Bibliografiske detaljer
Udgivet i:Front Neurosci
Main Authors: Chen, Shuang, Zou, Qin, Guo, Qiang, Chen, Yongmin, Kuang, Xi, Zhang, Yukang, Liu, Yan, Wu, Wengang, Li, Ge, Tu, Linzhi, Tong, Jingyi, Li, Songrong, Ma, Lin, Li, Qifu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7874057/
https://ncbi.nlm.nih.gov/pubmed/33584170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.581441
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