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A guide to creating design matrices for gene expression experiments

Differential expression analysis of genomic data types, such as RNA-sequencing experiments, use linear models to determine the size and direction of the changes in gene expression. For RNA-sequencing, there are several established software packages for this purpose accompanied with analysis pipeline...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:F1000Res
Hauptverfasser: Law, Charity W., Zeglinski, Kathleen, Dong, Xueyi, Alhamdoosh, Monther, Smyth, Gordon K., Ritchie, Matthew E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000 Research Limited 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873980/
https://ncbi.nlm.nih.gov/pubmed/33604029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.27893.1
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