Integrin Alpha E (CD103) Limits Virus-Induced IFN-I Production in Conventional Dendritic Cells

Early and strong production of IFN-I by dendritic cells is important to control vesicular stomatitis virus (VSV), however mechanisms which explain this cell-type specific innate immune activation remain to be defined. Here, using a genome wide association study (GWAS), we identified Integrin alpha-E...

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Gepubliceerd in:Front Immunol
Hoofdauteurs: Duhan, Vikas, Khairnar, Vishal, Kitanovski, Simo, Hamdan, Thamer A., Klein, Andrés D., Lang, Judith, Ali, Murtaza, Adomati, Tom, Bhat, Hilal, Friedrich, Sarah-Kim, Li, Fanghui, Krebs, Philippe, Futerman, Anthony H., Addo, Marylyn M., Hardt, Cornelia, Hoffmann, Daniel, Lang, Philipp A., Lang, Karl S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873973/
https://ncbi.nlm.nih.gov/pubmed/33584680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.607889
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