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Extracellular ATP Mediates Cancer Cell Migration and Invasion Through Increased Expression of Cyclooxygenase 2

The tumor microenvironment plays a major role in the ability of the tumor cells to undergo metastasis. A major player of tumors gaining metastatic property is the inflammatory protein, cyclooxygenase 2 (COX-2). Several tumors show upregulation of this protein, which has been implicated in mediating...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Sharma, Shilpa, Kalra, Harshit, Akundi, Ravi Shankar
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873692/
https://ncbi.nlm.nih.gov/pubmed/33584298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.617211
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