Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP level increase

Cancer cells are able to uptake extracellular ATP (eATP) via macropinocytosis to elevate intracellular ATP (iATP) levels, enhancing their survival in drug treatment. However, the involved drug resistance mechanisms are unknown. Here we investigated the roles of eATP as either an energy or a phosphor...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Xuan, Li, Yunsheng, Qian, Yanrong, Cao, Yanyang, Shriwas, Pratik, Zhang, Haiyun, Chen, Xiaozhuo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675678/
https://ncbi.nlm.nih.gov/pubmed/29152126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21231
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