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Extracellular ATP, as an energy and phosphorylating molecule, induces different types of drug resistances in cancer cells through ATP internalization and intracellular ATP level increase

Cancer cells are able to uptake extracellular ATP (eATP) via macropinocytosis to elevate intracellular ATP (iATP) levels, enhancing their survival in drug treatment. However, the involved drug resistance mechanisms are unknown. Here we investigated the roles of eATP as either an energy or a phosphor...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wang, Xuan, Li, Yunsheng, Qian, Yanrong, Cao, Yanyang, Shriwas, Pratik, Zhang, Haiyun, Chen, Xiaozhuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675678/
https://ncbi.nlm.nih.gov/pubmed/29152126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21231
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