Inactivation of N-Acetylglucosaminyltransferase I and α1,3-Fucosyltransferase Genes in Nicotiana tabacum BY-2 Cells Results in Glycoproteins With Highly Homogeneous, High-Mannose N-Glycans

Nicotiana tabacum Bright Yellow-2 (BY-2) suspension cells are among the most commonly used plant cell lines for producing biopharmaceutical glycoproteins. Recombinant glycoproteins are usually produced with a mix of high-mannose and complex N-glycans. However, N-glycan heterogeneity is a concern for...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Front Plant Sci
Main Authors: Herman, Xavier, Far, Johann, Courtoy, Adeline, Bouhon, Laurent, Quinton, Loïc, De Pauw, Edwin, Chaumont, François, Navarre, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Plant Science
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873608/
https://ncbi.nlm.nih.gov/pubmed/33584780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpls.2021.634023
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares