Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs

A subset of CD4 + lymphocytes, regulatory T cells (Tregs), are necessary for central tolerance and function as suppressors of autoimmunity against self-antigens. The SRC-3 coactivator is an oncogene in multiple cancers and is capable of potentiating numerous transcription factors in a wide variety o...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nikolai, Bryan C., Jain, Prashi, Cardenas, David L., York, Brian, Feng, Qin, McKenna, Neil J., Dasgupta, Subhamoy, Lonard, David M., O’Malley, Bert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873281/
https://ncbi.nlm.nih.gov/pubmed/33564037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82945-3
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