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The secreted inhibitor of invasive cell growth CREG1 is negatively regulated by cathepsin proteases

Previous clinical and experimental evidence strongly supports a breast cancer-promoting function of the lysosomal protease cathepsin B. However, the cathepsin B-dependent molecular pathways are not completely understood. Here, we studied the cathepsin-mediated secretome changes in the context of the...

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Détails bibliographiques
Publié dans:Cell Mol Life Sci
Auteurs principaux: Gomez-Auli, Alejandro, Hillebrand, Larissa Elisabeth, Christen, Daniel, Günther, Sira Carolin, Biniossek, Martin Lothar, Peters, Christoph, Schilling, Oliver, Reinheckel, Thomas
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7873128/
https://ncbi.nlm.nih.gov/pubmed/32385587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03528-5
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