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Safety and Efficacy of Sovateltide (IRL-1620) in a Multicenter Randomized Controlled Clinical Trial in Patients with Acute Cerebral Ischemic Stroke

BACKGROUND: Sovateltide (IRL-1620, PMZ-1620), an endothelin-B receptor agonist, has been previously shown to increase cerebral blood flow, have anti-apoptotic activity and produce neurovascular remodeling when administered intravenously following acute cerebral ischemic stroke in rats. Its safety an...

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Detalhes bibliográficos
Publicado no:CNS Drugs
Main Authors: Gulati, Anil, Agrawal, Nilesh, Vibha, Deepti, Misra, U. K., Paul, Birinder, Jain, Dinesh, Pandian, Jeyaraj, Borgohain, Rupam
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872992/
https://ncbi.nlm.nih.gov/pubmed/33428177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40263-020-00783-9
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