Attenuation of opioid tolerance by ET(B) receptor agonist, IRL-1620, is independent of an accompanied decrease in nerve growth factor in mice

AIM: ET(A) receptor antagonists reverse opioid tolerance but the involvement of ET(B) receptors is unknown. In morphine or oxycodone tolerant mice we investigated (1) the effect of ET(B) receptor agonist, IRL-1620, on analgesic tolerance; (2) changes in expression of the brain ET(A) and ET(B) recept...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Gulati, Shruti, Briyal, Seema, Jones, Shantel, Bhalla, Shaifali, Gulati, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466593/
https://ncbi.nlm.nih.gov/pubmed/28626808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2017.e00317
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