Berberine Protects Against NLRP3 Inflammasome via Ameliorating Autophagic Impairment in MPTP-Induced Parkinson’s Disease Model

The NLR family pyrin domain containing 3 (NLRP3) inflammasome was reported to be regulated by autophagy and activated during inflammatory procession of Parkinson’s disease (PD). Berberine (BBR) is well-studied to play an important role in promoting anti-inflammatory response to mediate the autophagy...

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Publicado en:Front Pharmacol
Main Authors: Huang, Shuxuan, Liu, Hanqun, Lin, Yuwan, Liu, Muchang, Li, Yanhua, Mao, Hengxu, Zhang, Zhiling, Zhang, Yunlong, Ye, Panghai, Ding, Liuyan, Zhu, Ziting, Yang, Xinling, Chen, Chaojun, Zhu, Xiaoqin, Huang, Xiaoyun, Guo, Wenyuan, Xu, Pingyi, Lu, Lin
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872967/
https://ncbi.nlm.nih.gov/pubmed/33584302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.618787
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