Association of LAG3 genetic variation with an increased risk of PD in Chinese female population

BACKGROUND: Emerging evidence suggests that α-synuclein (α-syn) aggregation and intercellular transmission contributes to pathogenesis of Parkinson’s disease (PD) and the toxic fibrillary α-syn binds lymphocyte-activation gene 3 (LAG3) receptor that mediates α-syn transmission. The deletion of LAG3...

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Vydáno v:J Neuroinflammation
Hlavní autoři: Guo, Wenyuan, Zhou, Miaomiao, Qiu, Jiewen, Lin, Yuwan, Chen, Xiang, Huang, Shuxuan, Mo, Mingshu, Liu, Hanqun, Peng, Guoyou, Zhu, Xiaoqin, Xu, Pingyi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6918662/
https://ncbi.nlm.nih.gov/pubmed/31847878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-019-1654-6
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