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GSK2593074A blocks progression of existing abdominal aortic dilation
OBJECTIVE: Receptor interacting proteins kinase 1 and 3 (RIPK1 and RIPK3) have been shown to play essential roles in the pathogenesis of abdominal aortic aneurysms (AAAs) by mediating necroptosis and inflammation. We previously discovered a small molecular inhibitor GSK2593074A (GSK’074) that binds...
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| Publicat a: | JVS Vasc Sci |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7872141/ https://ncbi.nlm.nih.gov/pubmed/33569546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvssci.2020.07.001 |
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