Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is associated with highly immunosuppressive tumor microenvironment (TME) that can limit the efficacy of dendritic cell (DC) vaccine immunotherapy. Irreversible electroporation (IRE) is a local ablation approach. Herein, we test the hypothesis that IRE ablation...

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Dades bibliogràfiques
Publicat a:Oncoimmunology
Autors principals: Yang, Jia, Eresen, Aydin, Shangguan, Junjie, Ma, Quanhong, Yaghmai, Vahid, Zhang, Zhuoli
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872063/
https://ncbi.nlm.nih.gov/pubmed/33643692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1875638
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