Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is associated with highly immunosuppressive tumor microenvironment (TME) that can limit the efficacy of dendritic cell (DC) vaccine immunotherapy. Irreversible electroporation (IRE) is a local ablation approach. Herein, we test the hypothesis that IRE ablation...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Yang, Jia, Eresen, Aydin, Shangguan, Junjie, Ma, Quanhong, Yaghmai, Vahid, Zhang, Zhuoli
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872063/
https://ncbi.nlm.nih.gov/pubmed/33643692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1875638
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