Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis

BACKGROUND: Synaptic failure is one of the principal events associated with cognitive dysfunction in Alzheimer’s disease (AD). Preservation of existing synapses and prevention of synaptic loss are promising strategies to preserve cognitive function in AD patients. As a potent natural anti-oxidant, a...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Maiti, Panchanan, Bowers, Zackary, Bourcier-Schultz, Ali, Morse, Jarod, Dunbar, Gary L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871397/
https://ncbi.nlm.nih.gov/pubmed/33557949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00769-9
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