Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis

BACKGROUND: Synaptic failure is one of the principal events associated with cognitive dysfunction in Alzheimer’s disease (AD). Preservation of existing synapses and prevention of synaptic loss are promising strategies to preserve cognitive function in AD patients. As a potent natural anti-oxidant, a...

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發表在:Alzheimers Res Ther
Main Authors: Maiti, Panchanan, Bowers, Zackary, Bourcier-Schultz, Ali, Morse, Jarod, Dunbar, Gary L.
格式: Artigo
語言:Inglês
出版: BioMed Central 2021
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871397/
https://ncbi.nlm.nih.gov/pubmed/33557949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-021-00769-9
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