The novel TRPA1 antagonist BI01305834 inhibits ovalbumin-induced bronchoconstriction in guinea pigs

BACKGROUND: Asthma is a chronic respiratory disease in which the nervous system plays a central role. Sensory nerve activation, amongst others via Transient Receptor Potential Ankyrin 1 (TRPA1) channels, contributes to asthma characteristics including cough, bronchoconstriction, mucus secretion, air...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: van den Berg, Mariska P. M., Nijboer-Brinksma, Susan, Bos, I. Sophie T., van den Berge, Maarten, Lamb, David, van Faassen, Martijn, Kema, Ido P., Gosens, Reinoud, Kistemaker, Loes E. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871391/
https://ncbi.nlm.nih.gov/pubmed/33557843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-021-01638-7
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