Transcription Factor Pit-1 Affects Transcriptional Timing in the Dual-Promoter Human Prolactin Gene

Gene transcription occurs in short bursts interspersed with silent periods, and these kinetics can be altered by promoter structure. The effect of alternate promoter architecture on transcription bursting is not known. We studied the human prolactin (hPRL) gene that contains 2 promoters, a pituitary...

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Bibliografiske detaljer
Udgivet i:Endocrinology
Main Authors: McNamara, Anne V, Awais, Raheela, Momiji, Hiroshi, Dunham, Lee, Featherstone, Karen, Harper, Claire V, Adamson, Antony A, Semprini, Sabrina, Jones, Nicholas A, Spiller, David G, Mullins, John J, Finkenstädt, Bärbel F, Rand, David, White, Michael R H, Davis, Julian R E
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871365/
https://ncbi.nlm.nih.gov/pubmed/33388754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa249
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