Spatially coordinated dynamic gene transcription in living pituitary tissue

Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue phenotype, but it has been a challenge to quantitatively analyse this in living cells over time, as opposed to studying snap-shots of gene ex...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Featherstone, Karen, Hey, Kirsty, Momiji, Hiroshi, McNamara, Anne V, Patist, Amanda L, Woodburn, Joanna, Spiller, David G, Christian, Helen C, McNeilly, Alan S, Mullins, John J, Finkenstädt, Bärbel F, Rand, David A, White, Michael RH, Davis, Julian RE
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4749562/
https://ncbi.nlm.nih.gov/pubmed/26828110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08494
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