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Whole exome sequencing identifies rare coding variants in novel human-mouse ortholog genes in African individuals diagnosed with non-syndromic hearing impairment

Physiologically, the human and murine hearing systems are very similar, justifying the extensive use of mice in experimental models for hearing impairment (HI). About 340 murine HI genes have been reported; however, whether variants in all human-mouse ortholog genes contribute to HI has been rarely...

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Detalles Bibliográficos
Publicado en:Exp Biol Med (Maywood)
Main Authors: Oluwole, Oluwafemi G, Esoh, Kevin K, Wonkam-Tingang, Edmond, Manyisa, Noluthando, Noubiap, Jean Jacques, Chimusa, Emile R, Wonkam, Ambroise
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871117/
https://ncbi.nlm.nih.gov/pubmed/32996353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220960388
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