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Whole exome sequencing identifies rare coding variants in novel human-mouse ortholog genes in African individuals diagnosed with non-syndromic hearing impairment

Physiologically, the human and murine hearing systems are very similar, justifying the extensive use of mice in experimental models for hearing impairment (HI). About 340 murine HI genes have been reported; however, whether variants in all human-mouse ortholog genes contribute to HI has been rarely...

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Dades bibliogràfiques
Publicat a:Exp Biol Med (Maywood)
Autors principals: Oluwole, Oluwafemi G, Esoh, Kevin K, Wonkam-Tingang, Edmond, Manyisa, Noluthando, Noubiap, Jean Jacques, Chimusa, Emile R, Wonkam, Ambroise
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871117/
https://ncbi.nlm.nih.gov/pubmed/32996353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220960388
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