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Whole exome sequencing identifies rare coding variants in novel human-mouse ortholog genes in African individuals diagnosed with non-syndromic hearing impairment

Physiologically, the human and murine hearing systems are very similar, justifying the extensive use of mice in experimental models for hearing impairment (HI). About 340 murine HI genes have been reported; however, whether variants in all human-mouse ortholog genes contribute to HI has been rarely...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Exp Biol Med (Maywood)
Κύριοι συγγραφείς: Oluwole, Oluwafemi G, Esoh, Kevin K, Wonkam-Tingang, Edmond, Manyisa, Noluthando, Noubiap, Jean Jacques, Chimusa, Emile R, Wonkam, Ambroise
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: SAGE Publications 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871117/
https://ncbi.nlm.nih.gov/pubmed/32996353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220960388
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