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VSG mRNA levels are regulated by the production of functional VSG protein

The bloodstream form of Trypanosoma brucei persists in mammalian hosts through a population survival strategy depending on antigenic variation of a cell surface coat composed of the variant surface glycoprotein (VSG). The integrity of the VSG coat is essential and blocking its synthesis results in a...

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Pubblicato in:Mol Biochem Parasitol
Autori principali: Maudlin, Isabella E., Kelly, Steve, Schwede, Angela, Carrington, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier/North-Holland Biomedical Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7871013/
https://ncbi.nlm.nih.gov/pubmed/33352254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2020.111348
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