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The VSG C-terminal domain is inaccessible to antibodies on live trypanosomes

In the mammalian host, the Trypanosoma brucei cell surface is covered with a densely packed protein coat of a single protein, the variant surface glycoprotein (VSG). The VSG is believed to shield invariant surface proteins from host antibodies but there is limited information on how far antibodies c...

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Detalhes bibliográficos
Main Authors: Schwede, Angela, Jones, Nicola, Engstler, Markus, Carrington, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier/North-Holland Biomedical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025347/
https://ncbi.nlm.nih.gov/pubmed/21074579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2010.11.004
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