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Microclusters as T Cell Signaling Hubs: Structure, Kinetics, and Regulation

When T cell receptors (TCRs) engage with stimulatory ligands, one of the first microscopically visible events is the formation of microclusters at the site of T cell activation. Since the discovery of these structures almost 20 years ago, they have been studied extensively in live cells using confoc...

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Publicat a:Front Cell Dev Biol
Autors principals: Balagopalan, Lakshmi, Raychaudhuri, Kumarkrishna, Samelson, Lawrence E.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7870797/
https://ncbi.nlm.nih.gov/pubmed/33575254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.608530
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