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Evaluation of the impact of renal impairment on the pharmacokinetics of glasdegib in otherwise healthy volunteers
PURPOSE: Glasdegib is being developed for indications in myeloid malignancies. The effect of renal impairment on the pharmacokinetics (PK) of a single, oral, 100-mg glasdegib dose under fasted conditions was assessed. METHODS: Open-label, parallel-group study (NCT03596567). Participants of good gene...
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| Udgivet i: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer Berlin Heidelberg
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7870595/ https://ncbi.nlm.nih.gov/pubmed/33388951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04207-9 |
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